Research opportunities in Ratz lab at Karolinska Institute
Michael Ratz (IMPRS MolBio Alumnus) is setting up the Ratz Lab at Karolinska Institute (Stockholm, Sweden) and has several openings for Master students, PhD students and postdocs to work at the intersection of neuroscience, synthetic biology, and single-cell (spatial) transcriptomics.
The lab is interested in the brain wiring problem: how is genomic information (thousands of genes) translated into neuron-specific connectivity (trillions of synapses)? To answer this fascinating question, they use and develop novel molecular barcoding and 3D intact-tissue RNA-seq tools that enable massively parallel neural circuit tracing with molecular detail. They study 1) how synaptic specificity is established amongst dozens of diverse neuron types during brain development and 2) how gene mutations affect neuronal wiring in mouse models of neurodevelopmental disorders such as autism.
Candidates with a background in experimental life sciences (e.g., molecular biology, (developmental) neuroscience) and/or data science (e.g., bioinformatics, computer science) are encouraged to apply.
If interested, please email your CV and a cover letter to Michael Ratz: michael.ratz@ki.se.